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Literature summary for 2.7.7.B22 extracted from
- Multimerization properties of PiggyMac, a domesticated piggyBac transposase involved in programmed genome rearrangements (2017), Nucleic Acids Res., 45, 3204-3216 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Paramecium tetraurelia | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PGM | - |
Paramecium tetraurelia |
| PiggyMac | - |
Paramecium tetraurelia |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | transposase Pgm is essential for DNA cleavage at ends of internal eliminated sequences. The DDD triad and the cysteine-rich domain are essential for Pgm activity and mutations in either domain have a dominant-negative effect in wild-type cells. A mutant lacking the cysteine-rich domain is partially active in the presence of limiting Pgm amounts, but inactive when Pgm is completely absent | Paramecium tetraurelia |
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Release 2023.1 (January 2023)
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